ISOLUTE® Si-Thiol

Chemical Name:
Silica 1-propanethiol; 3-Mercaptopropyl silica gel (Si-Thiol; Si-SH)

Solid-support Type:
Silica

Typical Capacity:
1.3 mmol/g

Size:
63 µm

Appearance:
Free flowing off-white powder

Compatible Solvents:
Dichloromethane (DCM), Methanol (MeOH), Ethanol (EtOH), Tetrahydrofuran (THF)

Typical Conditions:
Add 4-6 equiv to crude reaction mixture. Stir for 15 min-2 h, then filter.

Applications:
Scavenger of electrophiles eg. alkyl-, benzyl- and allyl- halides, acid chlorides, isocyanates; Metal scavenger eg Pd, Pt, Cu, Hg, Ag and Pb